Life Science · 生命科学

Medical device documentation
that survives regulatory review

IFU, 510(k) material, CE/MDR technical files, SOPs and clinical protocols — translated against the governing standard, with a documented and traceable process.

Why this is harder than it looks

01

The submitted wording is itself under review

In a regulatory submission the text is not a wrapper around the evidence — it is part of the evidence. Reviewers read what you filed. An ambiguous rendering of an indication, a contraindication or a performance claim becomes a question to answer, and questions cost review cycles.

02

Terms have to match the standard, not just be accurate

Regulated terminology is defined by the governing standard and by your own device labelling. A defensible synonym is still the wrong word if the standard and your label use another. Consistency with the source document set matters as much as linguistic quality.

03

Untraceable output is a compliance problem

A quality system requires a documented process with accountable steps. Text of unclear provenance — including unreviewed machine output — is difficult to defend during an audit, regardless of whether it happens to be correct.

Documents we handle

  • IFU (Instructions For Use)
  • 510(k) submission material
  • CE/MDR technical file
  • SOP
  • Clinical protocol
  • Labelling & packaging
  • Risk management file
  • CAPA documentation

What governs the work

EU MDR 2017/745
Member states determine the language(s) required for IFU and labelling in their market. Requirements are per-market, not EU-wide.
FDA submissions
Filed in English. Where source documentation, clinical data or QMS records were authored in another language, accurate English rendering is required.
ISO 13485 / ISO 9001:2015
A documented, auditable translation process with defined review steps.

How a life science project runs

01
Client Upload
Files, reference material and any existing termbase
02
AI Translation
Draft generation on a domain-tuned engine
03
Terminology Mapping
Terms locked against the project termbase
04
Expert Review Human QA
Domain specialist validates accuracy and context
05
QA
LISA QA 3.1 audit against defined error categories
06
Delivery
Format restored, delivered in the original layout
07
Knowledge Asset Update Compounding asset
Terminology fed back — every project improves the next
Recommended service levelL3 — Angel PremiumRegulatory filings are expert-led and LISA QA 3.1 audited. This content is never delivered as reviewed machine output alone.

Selected work

Life ScienceFDA registration

US market entry for an IVD diagnostics firm

Challenge An in-vitro diagnostics company entering the US market needed its full FDA registration documentation translated to a standard that would withstand regulatory review.

Solution Expert-led translation by reviewers with biomedical background, following a documented and traceable process, accompanied by a written quality-assurance letter.

  • FDA registration cleared on first pass
  • Written quality-assurance letter provided
  • Clinical-background reviewers throughout

Life Science terminology

Bilingual reference for terms that appear in this documentation.

IFU使用说明510(k)上市前通知MDR医疗器械法规CAPA纠正预防措施Biocompatibility生物相容性ISO 13485质量管理体系GMP良好生产规范PMA上市前批准Adverse Event不良事件Bioburden生物负载Sterility无菌Excipient辅料Pharmacovigilance药物警戒Indication适应症Contraindication禁忌症Predicate Device对照器械Clinical Endpoint临床终点Lot Number批号Shelf Life有效期IVD体外诊断GxP良好规范Batch Record批记录Validation验证Traceability可追溯性Sterilization灭菌Nonconformance不符合项Risk Management风险管理Usability Engineering可用性工程Post-Market Surveillance上市后监督Notified Body公告机构Declaration of Conformity符合性声明Active Ingredient活性成分Stability Study稳定性研究Reagent试剂Labeling标签标识Adjuvant佐剂Assay检测法cGMP现行良好生产规范Change Control变更控制Deviation偏差Quarantine隔离待检Potency效价Impurity杂质In Vivo体内Bioequivalence生物等效性Cold Chain冷链Titration滴定Bioavailability生物利用度UDI唯一器械标识Biomarker生物标志物Informed Consent知情同意Adverse Reaction不良反应Recall召回Placebo安慰剂Temperature Excursion温度偏移Bioburden Testing生物负载测试Endotoxin内毒素Master Batch Record主批记录Design History File设计历史文档Technical File技术文件Summative Evaluation总结性评价Vigilance Reporting警戒报告Aseptic Processing无菌工艺Cleanroom洁净室Corrective Action纠正措施Preventive Action预防措施Design Control设计控制Retest Date复验期Investigational Product试验用产品Case Report Form病例报告表Protocol Amendment方案修订Serious Adverse Event严重不良事件Certificate of Analysis分析证书Unique Formula Identifier唯一配方标识Marketing Authorization上市许可Summary of Product Characteristics产品特性摘要Clinical Investigation Plan临床研究计划Serialization序列化Extractables and Leachables可提取物与浸出物Container Closure System容器密封系统Real-World Evidence真实世界证据Good Clinical Practice药物临床试验质量管理规范Clinical Study Report临床研究报告Nitrosamine Impurity亚硝胺杂质Comparator Product对照药Site Master File场所主文件Common Technical Document通用技术文档Drug Master File药物主文件Investigator Brochure研究者手册Pharmacokinetics药代动力学Process Validation工艺验证Cleaning Validation清洁验证
Full terminology glossary →
“Documentation submitted to Europe for review is held to a very high standard. Angel recommended using English as the source language and having native-speaker translators handle it — the result met our expectations, and they were willing to take our experts’ feedback and revise patiently.”
Johnson & JohnsonLife Science

Life Science questions

FDA submissions are made in English. The translation requirement arises when your underlying technical documentation, clinical data, design history or quality records were authored in another language — those need accurate, defensible English rendering. Confirm the specifics of your pathway with your regulatory consultant; requirements differ by device class and submission type.
Under MDR 2017/745, instructions for use and labelling must be provided in the language(s) accepted by each member state where the device is placed on the market, and each member state determines that for its own territory. In practice this means planning for a set of languages defined by your target markets rather than a single EU version. Verify the current list for your markets with your notified body.
Projects are matched to reviewers with relevant domain background rather than distributed to whoever is available. For device documentation that means someone who can judge whether a clinical or technical term is used correctly in context — the judgement a general linguist cannot reliably make.
Send us your approved labelling, previous submissions or existing termbase at kickoff. Those terms are locked before review begins, so the translation aligns with what you have already filed instead of introducing a new vocabulary that a reviewer has to reconcile.
AI is used to generate the draft, never as the deliverable. Every regulatory document goes through domain expert review and a LISA QA 3.1 audit before delivery. The position is deliberate: AI raises efficiency, experts ensure quality, and Angel takes responsibility for what is delivered.
Under NDA covering everyone in the delivery chain, including reviewers. If your protocol requires specific handling, retention or destruction terms, raise it at kickoff so it is built into the project rather than retrofitted.

Send us a life science document

Acknowledged in 4 hours, quoted in 24. Under NDA from the first upload.